New advances in signaling and pattern formation.

نویسنده

  • Nicholas S Tolwinski
چکیده

Drosophila, Wnt, FGF, Jak/Stat, Rho, Rac, RhoGEF, Pebble, Naked Cuticle The site for the latest installment of the Fly Meeting (March 7–11) was downtown Philadelphia. The conference offered an illustration of all that is great about the Drosophila field bringing together evolutionary biologists, immunologists and everyone in between. Here I will provide a small sample of several advances from the pattern formation platform section. This is a topic of great importance as it deals with the in vivo readout of the many different signaling pathways that have been linked to disease in humans, and offers many interesting intellectual challenges.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Recent Advances in T Cell Signaling in Aging

The immune system of mammalian organisms undergoes alterations that may account for an increased susceptibility to certain infections, autoimmune diseases, or malignancies. Well characterized are age related defect in T cell functions and cell mediated immunity. Although it is well established that the functional properties of T cells decrease with age, its biochemical and molecular nature is...

متن کامل

GAME OF COORDINATION FOR BACTERIAL PATTERN FORMATION: A FINITE AUTOMATA MODELLING

In this paper, we use game theory to describe the emergence of self-organization and consequent pattern formation through communicative cooperation in Bacillus subtilis colonies. The emergence of cooperative regime is modelled as an n-player Assurance game, with the bacterial colonies as individual players. The game is played iteratively through cooperative communication, and mediated by exchan...

متن کامل

Induction of secondary axis in hydra revisited: New insights into pattern formation

In 1909, several years before the famous `Organizer’ experiments of Spemann and Mangold, Ethel Browne demonstrated induction of a secondary axis in hydra by grafting a hypostome. Based on this and subsequent work, in the late sixties, Lewis Wolpert proposed the theory of morphogen gradients and positional information. We have studied secondary axis induction by hypostome and foot tissue using t...

متن کامل

Long non-coding RNA FOXO1 inhibits lung cancer cell growth through down-regulating PI3K/AKT signaling pathway

Objective(s): Lung cancer is one of the most common malignant tumors, which seriously threatens the health and life of the people. Recently, a novel long non-coding RNA (lncRNA) termed lncFOXO1 was found and investigated in breast cancer. However, the effect of lncFOXO1 on lung cancer is still ambiguous. The current study aimed to uncover the functions of lncFOXO1 in l...

متن کامل

A New Colorimetric Azo-azomethine Probe for Fluoride Ion Detection Based on the Proton Transfer Signaling Mode: Real-life Applications

Four novel receptors were designed and synthesized for colorimetric detection of F− ions. The introduction of four electron withdrawing groups into the backbone of the receptors makes the two phenolic groups efficient hydrogen bonding sites. The binding properties of receptors with anions were examined for the first time by UV–Vis, 1H NMR and fluorescence spectroscopies. The addition of F− resu...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Fly

دوره 1 2  شماره 

صفحات  -

تاریخ انتشار 2007